Pharmacogenomics (PGx) is a rapidly advancing field within precision medicine, focusing on the relationship between genetic variations and drug metabolism. The adoption of PGx in clinical and diagnostic settings is gaining momentum as knowledgebases and genetic insights continue to improve. At Geneyx, we recognize the significance of this field and are committed to offering a comprehensive PGx workflow to our users.

The Geneyx PGx workflow provides thorough interpretations for 13 CPIC level A/B genes that influence the metabolism of 68 commonly prescribed drugs. This information is curated from multiple reliable annotation sources, including the Clinical Pharmacogenomic Implementation Consortium (CPIC), the Food and Drug Administration (FDA), and the Pharmacogenomics Knowledge Base (PharmGKB). Each reported gene is accompanied by useful hyperlinks to these databases, allowing easy access to additional information, all of which is automatically integrated into the report.

The Geneyx PGx report delivers detailed patient and drug information in a user-friendly and customizable format. Genes with low quality or missing SNPs can be conveniently excluded from the report. Moreover, final modifications to the report can be made using the report editor, and electronic signature sign-off ensures compliance and accountability. The report presents the gene name, genotype, and the impact of genetic variations on drug metabolism. Additionally, gene descriptions elucidate the gene’s function, its association with drug metabolism, and the effect of genetic changes on therapeutic efficacy.

By leveraging key databases and unique genetic profiles, the Geneyx Pharmacogenomics workflow equips users with powerful insights to mitigate potential adverse drug reactions and metabolic responses. If you are affiliated with a clinical or diagnostic company and are interested in providing PGx reports to your patients, we invite you to schedule a meeting with us to experience the Geneyx PGx workflow in real time.

The PGx protocol requires have a PGx license to use.